Aminoglycosides, “loop” diuretics, drugs that reduce tubular secretion, increase nephrotoxicity.
Incompatible with ethanol (inhibits atsetaldegidrogenazu) develop disulfiramopodobnye reactions (abdominal pain, facial flushing, headache, decreased blood pressure, nausea, vomiting, palpitations, sweating).
The solution is pharmaceutically incompatible with metribolone dosage aminoglycosides.
Patients who had a history of allergic reaction to penicillin, may be sensitive to cephalosporin antibiotics.
During treatment with cefamandole possible: false-positive direct Coombs’ test, false positive reaction of urine for glucose, proteinuria.
In elderly and debilitated patients with a deficiency there is an increased the risk of hypoprothrombinemia with or without bleeding (in these cases shows the introduction of vitamin K).
During treatment should refrain from receiving ethanol – possible effects, similar to the action of disulfiram (facial flushing, abdominal cramps and in the stomach, nausea, vomiting, . headache, decrease blood pressure, tachycardia, dyspnea)
a freshly prepared solution unfit for use within 24 hours when stored at room temperature and for 96 hours – when stored in the refrigerator.
of 0.5 g and 1.0 g of the active metribolone dosage substance in glass bottles with a capacity of 10 ml.
In 1 or 5 vials in a cardboard box with the instructions for medical use.
In 1 or 5 vials in blisters together with the solvent ( water for injections). Every contour packing in a cardboard box with the instructions for medical use.
1 bottle together with the solvent in a stack of cardboard packaging without contour. In one pack put the instructions for use.
On 50 vials are placed in a cardboard box with a 1-5 instructions for use metribolone dosage (for hospitals).